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The Corner returns with mix of old and new

The Wilson Times
WAKE FOREST — Since 1897, The Corner has always been, well, on the corner, there where North Avenue meets North Main Street.
57 months ago

Fetal hypoplastic lungs have multilineage inflammation that is reversed by amniotic fluid stem cell extracellular vesicle treatment

Science | AAAS
Antenatal administration of extracellular vesicles from amniotic fluid stem cells (AFSC-EVs) reverses features of pulmonary hypoplasia in models of congenital...
2 months ago

Reactive astrocytes secrete the chaperone HSPB1 to mediate neuroprotection

Science | AAAS
Molecular chaperones are protective in neurodegenerative diseases by preventing protein misfolding and aggregation, such as extracellular...
6 months ago

Combining DNMT and HDAC6 inhibitors increases anti-tumor immune signaling and decreases tumor burden in ovarian cancer

Nature
Novel therapies are urgently needed for ovarian cancer, the deadliest gynecologic malignancy. Ovarian cancer has thus far been refractory to...
55 months ago

Clonal haematopoiesis and dysregulation of the immune system

Nature
Age-related diseases are frequently linked to pathological immune dysfunction, including excessive inflammation, autoreactivity and...
18 months ago

An independent regulator of global release pathways in astrocytes generates a subtype of extracellular vesicles required for postsynaptic function

Science | AAAS
Extracellular vesicles (EVs) are heterogeneous in size, composition, and function. We show that the six-transmembrane protein...
15 months ago

Water-soluble extracellular vesicle probes based on conjugated oligoelectrolytes

Science | AAAS
We developed a series of transmembrane conjugated oligoelectrolytes (COEs) with tunable optical emissions from the UV to the near IR to address the false-...
20 months ago

Cancer-associated fibroblasts produce matrix-bound vesicles that influence endothelial cell function

Science | AAAS
Cancer-associated fibroblasts promote tumor growth, in part, by releasing extracellular vesicles, which can carry proteins to cells in the tumor...
6 months ago

Circadian regulation of protein cargo in extracellular vesicles

Science | AAAS
The circadian clock controls many aspects of physiology, but it remains undescribed whether extracellular vesicles (EVs), including exosomes...
29 months ago

Extracellular vesicles as central regulators of blood vessel function in cancer

Science | AAAS
Blood vessels deliver oxygen and nutrients that sustain tumor growth and enable the dissemination of cancer cells to distant sites and the...
24 months ago